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Anatomy & Physiology

A practical map of the body's structures and systems

Lesson 10 of 20

Muscle fibers & contraction

Skeletal muscle produces movement and helps maintain posture and heat. Its fibers contain myofibrils built from repeating contractile units. Contraction occurs when actin and myosin interact, with calcium and ATP supporting the cycle. A muscle can generate tension while shortening, lengthening, or holding its length.

Key points

  • Slow oxidative fibers resist fatigue and support sustained activity; fast fibers can generate force rapidly.
  • A motor unit is a motor neuron and the muscle fibers it activates.
  • Calcium exposes binding sites on actin; myosin cross-bridges pull using energy from ATP.
  • Concentric contraction shortens while producing force; eccentric contraction lengthens under tension.
  • Isometric contraction produces tension without noticeable change in muscle length.
  • Muscle force is graded through motor-unit recruitment and firing rate.

Key terms

Sarcomere
Repeating contractile unit within a striated muscle fiber.
Actin
Thin filament that interacts with myosin during contraction.
Myosin
Motor protein whose heads bind to actin and generate force.
Motor unit
One motor neuron and all muscle fibers it innervates.
Eccentric contraction
Force-producing contraction while a muscle lengthens.
Isometric contraction
Force production without appreciable change in muscle length.

Memory tip

Concentric shortens, eccentric lengthens under load, isometric holds.

Clinical note

The sliding-filament model describes microscopic interaction; it does not mean filaments themselves shrink.

Unit checkpoint

Lock it in: match the terms, then test yourself.